5EEQ
Grb7 SH2 with the G7-B1 bicyclic peptide inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Growth factor receptor-bound protein 7 | polymer | 120 | 13690.7 | 2 | UniProt (Q14451) Pfam (PF00017) In PDB | Homo sapiens (human) | B47,Epidermal growth factor receptor GRB-7,GRB7 adapter protein |
| 2 | L, M | Bicyclic Peptide Inhibitor | polymer | 11 | 1378.5 | 2 | synthetic construct | ||
| 3 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 4 | water | water | 18.0 | 170 | Chemie (HOH) |
Sequence modifications
A, B: 415 - 532 (UniProt: Q14451)
| PDB | External Database | Details |
|---|---|---|
| Gly 413 | - | expression tag |
| Ser 414 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 30138.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 189.9 | |
| All* | Total formula weight | 30328.3 |
