Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007165 | biological_process | signal transduction |
| B | 0007165 | biological_process | signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 A 601 |
| Chain | Residue |
| A | ARG438 |
| A | ARG458 |
| A | SER460 |
| A | GLN461 |
| A | ARG462 |
| A | HOH703 |
| A | HOH724 |
| L | TYR5 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 B 601 |
| Chain | Residue |
| B | ARG458 |
| B | SER460 |
| B | GLN461 |
| B | ARG462 |
| B | HOH704 |
| B | HOH721 |
| M | TYR5 |
| B | ARG438 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for Ligand residues 48V L 12 through PRO L 10 bound to SER L 1 |
| Chain | Residue |
| L | SER1 |
| L | PHE2 |
| L | ASN7 |
| L | PHE9 |
| L | HOH105 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for Ligand 73C L 11 bound to SER L 1 |
| Chain | Residue |
| A | MET495 |
| A | ASP496 |
| L | SER1 |
| L | PHE2 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for Ligand 73C L 11 bound to SER L 8 |
| Chain | Residue |
| A | MET495 |
| A | ASP496 |
| L | SER1 |
| L | PHE2 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for Ligand 73C M 11 bound to SER M 1 |
| Chain | Residue |
| B | MET495 |
| B | ASP496 |
| M | SER1 |
| M | PHE2 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for Ligand residues 48V M 12 through PRO M 10 bound to SER M 1 |
| Chain | Residue |
| B | ARG427 |
| B | THR428 |
| M | SER1 |
| M | PHE2 |
| M | ASN7 |
| M | PHE9 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for Ligand 73C M 11 bound to SER M 8 |
| Chain | Residue |
| B | MET495 |
| B | ASP496 |
| M | SER1 |
| M | PHE2 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 192 |
| Details | Domain: {"description":"SH2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00191","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for dimerization and for HRAS activation"} |
