5E8D
Crystal structure of human epiregulin in complex with the Fab fragment of murine monoclonal antibody 9E5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Proepiregulin | polymer | 75 | 8254.3 | 1 | UniProt (O14944) | Homo sapiens (Human) | |
| 2 | B (H) | anti-human epiregulin antibody 9E5 Fab heavy chain | polymer | 220 | 23528.4 | 1 | Mus musculus | ||
| 3 | C (L) | anti-human epiregulin antibody 9E5 Fab light chain | polymer | 213 | 23606.2 | 1 | Mus musculus | ||
| 4 | D (H) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E, F (H, L) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | G, H (H, L) | water | water | 18.0 | 37 | Chemie (HOH) |
Sequence modifications
A: -24 - 46 (UniProt: O14944)
| PDB | External Database | Details |
|---|---|---|
| Gly -28 | - | expression tag |
| Pro -27 | - | expression tag |
| Ala -26 | - | expression tag |
| Met -25 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 55388.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 219.6 | |
| All* | Total formula weight | 55608.5 |
