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5E7D

Crystal Structure of the fifth bromodomain of human PB1 in complex with a hydroxyphenyl ligand

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DProtein polybromo-1polymer12414648.04UniProt (Q86U86)
Pfam (PF00439)
In PDB
Homo sapiens (Human)hPB1,BRG1-associated factor 180,BAF180,Polybromo-1D, PB1
2A, B, C, D(2E)-3-(dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-onenon-polymer191.24Chemie (5KL)
3D1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
4waterwater18.0232Chemie (HOH)
Sequence modifications
A, B, C, D: 613 - 734 (UniProt: Q86U86)
PDBExternal DatabaseDetails
Ser 611-expression tag
Met 612-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight58592.0
Non-Polymers*Number of molecules5
Total formula weight827.0
All*Total formula weight59419.0
*Water molecules are not included.

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PDB entries from 2024-07-31

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