5E7D
Crystal Structure of the fifth bromodomain of human PB1 in complex with a hydroxyphenyl ligand
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Protein polybromo-1 | polymer | 124 | 14648.0 | 4 | UniProt (Q86U86) Pfam (PF00439) | Homo sapiens (Human) | hPB1,BRG1-associated factor 180,BAF180,Polybromo-1D, PB1 |
| 2 | E, F, G, H (A, B, C, D) | (2E)-3-(dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-one | non-polymer | 191.2 | 4 | Chemie (5KL) | |||
| 3 | I (D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | J, K, L, M (A, B, C, D) | water | water | 18.0 | 232 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 613 - 734 (UniProt: Q86U86)
| PDB | External Database | Details |
|---|---|---|
| Ser 611 | - | expression tag |
| Met 612 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 58592.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 827.0 | |
| All* | Total formula weight | 59419.0 |
