4ZCS
Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase in complex with CDP-choline
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, C, E, B, D...) | Choline-phosphate cytidylyltransferase | polymer | 180 | 20810.1 | 6 | UniProt (Q8IEE9) Pfam (PF01467) | Plasmodium falciparum (isolate 3D7) | |
| 2 | G, H, I, J, L... (A, C, E, B, D...) | [2-CYTIDYLATE-O'-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM | non-polymer | 488.3 | 6 | Chemie (CDC) | |||
| 3 | K, M (B, D) | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL | non-polymer | 326.4 | 2 | Chemie (P33) | |||
| 4 | O, P, Q, R, S... (A, C, E, B, D...) | water | water | 18.0 | 341 | Chemie (HOH) |
Sequence modifications
A, C, E, B, D, F: 581 - 775 (UniProt: Q8IEE9)
| PDB | External Database | Details |
|---|---|---|
| Gly 578 | - | expression tag |
| His 579 | - | expression tag |
| Met 580 | - | expression tag |
| - | Lys 720 | deletion |
| - | Lys 721 | deletion |
| - | Lys 722 | deletion |
| - | Lys 723 | deletion |
| - | Lys 724 | deletion |
| - | Lys 725 | deletion |
| - | Ser 726 | deletion |
| - | Lys 727 | deletion |
| - | Gly 728 | deletion |
| - | Lys 729 | deletion |
| - | Ser 730 | deletion |
| - | Phe 731 | deletion |
| - | Ser 732 | deletion |
| - | Phe 733 | deletion |
| - | Asp 734 | deletion |
| - | Glu 735 | deletion |
| - | Glu 736 | deletion |
| - | Asn 737 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 124860.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3582.7 | |
| All* | Total formula weight | 128443.4 |
