4Z47
Structure of the enzyme-product complex resulting from TDG action on a GU mismatch in the presence of excess base
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | G/T mismatch-specific thymine DNA glycosylase | polymer | 204 | 23070.7 | 1 | UniProt (Q13569) Pfam (PF03167) In PDB | Homo sapiens (Human) | Thymine-DNA glycosylase,hTDG |
2 | C | DNA | polymer | 28 | 8646.6 | 1 | synthetic construct | ||
3 | D | DNA | polymer | 28 | 8473.4 | 1 | synthetic construct | ||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
5 | A | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
6 | water | water | 18.0 | 273 | Chemie (HOH) |
Sequence modifications
A: 111 - 308 (UniProt: Q13569)
PDB | External Database | Details |
---|---|---|
Gly 105 | - | expression tag |
Ser 106 | - | expression tag |
His 107 | - | expression tag |
Met 108 | - | expression tag |
Ala 109 | - | expression tag |
Ser 110 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 40190.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 246.3 | |
All* | Total formula weight | 40436.9 |