4Z2B
The structure of human PDE12 residues 161-609 in complex with GSK3036342A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2',5'-phosphodiesterase 12 | polymer | 455 | 51137.7 | 1 | UniProt (Q6L8Q7) Pfam (PF21171) Pfam (PF03372) | Homo sapiens (Human) | 2-PDE,Mitochondrial deadenylase |
| 2 | B (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 3 | C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | E (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 5 | F (A) | 3-(6-{[(2S,3S)-3-(hydroxymethyl)-2-phenylmorpholin-4-yl]carbonyl}-1-methyl-1H-benzimidazol-2-yl)-1H-indole-6-carbonitrile | non-polymer | 491.5 | 1 | Chemie (4LC) | |||
| 6 | G (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | H (A) | water | water | 18.0 | 462 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51137.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 858.2 | |
| All* | Total formula weight | 51995.9 |
