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4XDJ

Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in an alternate conformation (FORM 2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DPOTASSIUM CHANNEL SUBFAMILY K MEMBER 10polymer28231060.14UniProt (P57789)
Pfam (PF07885)
In PDB
homo sapiens (human)
2A, CPOTASSIUM IONnon-polymer39.16Chemie (K)
3A, B1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINEnon-polymer790.14Chemie (PC1)
4A, B, C, DTRIDECANEnon-polymer184.44Chemie (TRD)
Sequence modifications
A, B, C, D: 67 - 340 (UniProt: P57789)
PDBExternal DatabaseDetails
Met 66-initiating methionine
Ala 341-expression tag
Glu 342-expression tag
Asn 343-expression tag
Leu 344-expression tag
Tyr 345-expression tag
Phe 346-expression tag
Gln 347-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight124240.4
Non-Polymers*Number of molecules14
Total formula weight4132.6
All*Total formula weight128373.1
*Water molecules are not included.

219140

PDB entries from 2024-05-01

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