4WXG

Crystal structure of L-Serine Hydroxymethyltransferase in complex with a mixture of L-Threonine and Glycine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Serine hydroxymethyltransferase	polymer	428	46543.5	2	UniProt (Q5M0B4) Pfam (PF00464) In PDB	Streptococcus thermophilus	Serine methylase
2	A, C	N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-threonine	non-polymer		350.3	2	Chemie (2BO)
3	A, C	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
4	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
5		water	water		18.0	392	Chemie (HOH)

Sequence modifications

A, C: 1 - 416 (UniProt: Q5M0B4)

PDB	External Database	Details
Met -11	-	initiating methionine
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	93087.1
Non-Polymers*	Number of molecules	5
	Total formula weight	838.6
All*	Total formula weight	93925.7

*Water molecules are not included.