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4WV6

Heterodimer of Importin alpha 1 with nuclear localization signal of TAF8

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AImportin subunit alpha-1polymer47150988.71UniProt (P52292)
Pfam (PF01749)
Pfam (PF00514)
Pfam (PF16186)
In PDB
Homo sapiens (Human)Karyopherin subunit alpha-2,RAG cohort protein 1,SRP1-alpha
2B, CTranscription initiation factor TFIID subunit 8polymer141672.12UniProt (Q7Z7C8)
In PDB
Homo sapiensProtein taube nuss,TBP-associated factor 43 kDa,TBP-associated factor 8,Transcription initiation factor TFIID 43 kDa subunit,hTAFII43
3A1,2-ETHANEDIOLnon-polymer62.112Chemie (EDO)
4waterwater18.0463Chemie (HOH)
Sequence modifications
A: 60 - 529 (UniProt: P52292)
PDBExternal DatabaseDetails
Gly 59-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54333.0
Non-Polymers*Number of molecules12
Total formula weight744.8
All*Total formula weight55077.8
*Water molecules are not included.

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PDB entries from 2024-04-24

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