4WUR
The crystal structure of the MERS-CoV papain-like protease (C111S) with human ubiquitin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Papain-like protease | polymer | 326 | 36155.5 | 1 | UniProt (K9N7C7) Pfam (PF08715) | Human coronavirus EMC (HCoV-EMC) | pp1ab,ORF1ab polyprotein |
| 2 | B (B) | Polyubiquitin-B | polymer | 76 | 8576.8 | 1 | UniProt (P0CG47) Pfam (PF00240) | Homo sapiens (Human) | |
| 3 | C, D (A) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 2 | Chemie (IPA) | |||
| 4 | E (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A: 1 - 320 (UniProt: K9N7C7)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Ser -4 | - | expression tag |
| His -3 | - | expression tag |
| Met -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 92 | Lys 1573 | conflict |
| Ser 111 | Cys 1592 | engineered mutation |
| Leu 236 | Ile 1717 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44732.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 185.6 | |
| All* | Total formula weight | 44918.0 |
