4WUR

The crystal structure of the MERS-CoV papain-like protease (C111S) with human ubiquitin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006508	biological_process	proteolysis
A	0008234	molecular_function	cysteine-type peptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue IPA A 401

Chain	Residue
A	HIS91
A	TRP93
A	SER145
A	THR146
A	ILE149

---

site_id	AC2
Number of Residues	2
Details	binding site for residue IPA A 402

Chain	Residue
A	TYR84
A	LYS87

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 403

Chain	Residue
A	CYS226
A	CYS228
A	CYS191
A	CYS194

---

Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
B	LYS27-ASP52

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	37
Details	Zinc finger: {"description":"C4-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00444","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Active site: {"description":"For PL-PRO activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00444","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00444","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---