4UV7
The complex structure of extracellular domain of EGFR and GC1118A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | EPIDERMAL GROWTH FACTOR RECEPTOR | polymer | 621 | 68667.2 | 1 | UniProt (P00533) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) | HOMO SAPIENS (HUMAN) | PROTO-ONCOGENE C-ERBB-1, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, EPIDERMAL GROWTH FACTOR RECEPTOR 1 |
| 2 | B (H) | GC1118A | polymer | 225 | 23980.7 | 1 | HOMO SAPIENS (HUMAN) | ||
| 3 | C (L) | GC1118A | polymer | 219 | 24214.9 | 1 | HOMO SAPIENS (HUMAN) | ||
| 4 | D (B) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | E, F (C, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 6 | G (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | H, I, J (A, H, L) | water | water | 18.0 | 370 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 116862.9 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1435.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 221.2 | |
| All* | Total formula weight | 118519.4 |
