4RHU
Crystal structures of Mycobacterium tuberculosis 6-oxopurine phosphoribosyltransferase which is a potential target for drug development against this disease
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Hypoxanthine-guanine phosphoribosyltransferase Hpt | polymer | 201 | 22140.9 | 6 | UniProt (I6YCM5) Pfam (PF00156) UniProt (by SIFTS) (P9WHQ9) | Mycobacterium tuberculosis | |
| 2 | G, I (A, B) | {[(2R)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid) | non-polymer | 441.3 | 2 | Chemie (3QE) | |||
| 3 | H, J, K, M, O... (A, B, C, D, E...) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 4 | L, N, P, R (C, D, E, F) | {[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid) | non-polymer | 441.3 | 4 | Chemie (45T) | |||
| 5 | U, V, W, X, Y... (A, B, C, D, E...) | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 132845.5 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2842.1 | |
| All* | Total formula weight | 135687.6 |
