4OYT
Crystal structure of ternary complex of Plasmodium vivax SHMT with D-serine and folinic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Serine hydroxymethyltransferase, putative | polymer | 442 | 49249.2 | 3 | UniProt (A5K8L9) Pfam (PF00464) | Plasmodium vivax | |
| 2 | D, H, K (A, B, C) | (2R)-2-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3-oxidanyl-propanoic acid | non-polymer | 334.2 | 3 | Chemie (1W9) | |||
| 3 | E, I, L (A, B, C) | N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid | non-polymer | 473.4 | 3 | Chemie (FON) | |||
| 4 | F, G, J (A, B) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | M (C) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 6 | N (C) | TRIFLUOROETHANOL | non-polymer | 100.0 | 1 | Chemie (ETF) | |||
| 7 | O, P, Q (A, B, C) | water | water | 18.0 | 268 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 147747.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 2921.4 | |
| All* | Total formula weight | 150668.9 |
