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4OVN

Voltage-gated Sodium Channel 1.5 (Nav1.5) C-terminal domain in complex with Calmodulin poised for activation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G, I
(A, B, C, D, E)
Calmodulinpolymer14917321.55UniProt (P62158)
Pfam (PF13499)
UniProt (by SIFTS) (P0DP23)
Homo sapiens (Human)CaM
2B, D, F, H, J
(F, G, H, I, J)
Sodium channel protein type 5 subunit alphapolymer15718643.05UniProt (Q14524)Homo sapiens (Human)HH1,Sodium channel protein cardiac muscle subunit alpha,Sodium channel protein type V subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.5
3AA, CA, DA, EA, FA...
(C, D, E, A, B)
MAGNESIUM IONnon-polymer24.318Chemie (MG)
4BA, IA, O, P, U
(H, J, A, F, G)
SULFATE IONnon-polymer96.15Chemie (SO4)
5T, Z
(B, C)
PHOSPHATE IONnon-polymer95.02Chemie (PO4)
6JA, KA, LA, MA, NA...
(A, F, B, G, C...)
waterwater18.062Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains10
Total formula weight179822.4
Non-Polymers*Number of molecules25
Total formula weight1107.7
All*Total formula weight180930.1
*Water molecules are not included.

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PDB entries from 2024-10-30

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