4OCT
Crystal structure of human ALKBH5 crystallized in the presence of Mn^{2+} and 2-oxoglutarate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | RNA demethylase ALKBH5 | polymer | 222 | 25339.0 | 2 | UniProt (Q6P6C2) Pfam (PF13532) | Homo sapiens (human) | Alkylated DNA repair protein alkB homolog 5, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5 |
| 2 | C, N (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, O (A, B) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 2 | Chemie (AKG) | |||
| 4 | AA, BA, CA, E, F... (B, A) | UNKNOWN ATOM OR ION | non-polymer | 23 | Chemie (UNX) | ||||
| 5 | DA, EA (A, B) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
A, B: 74 - 294 (UniProt: Q6P6C2)
| PDB | External Database | Details |
|---|---|---|
| Gly 73 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 50678.0 | |
| Non-Polymers* | Number of molecules | 27 |
| Total formula weight | 402.1 | |
| All* | Total formula weight | 51080.1 |
