4NN6
Cytokine receptor complex - Crystal form 1B
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Thymic stromal lymphopoietin | polymer | 130 | 15109.9 | 1 | UniProt (Q9JIE6) Pfam (PF15216) In PDB | Mus musculus (mouse) | TSLP, Thymic stroma-derived lymphopoietin |
2 | B | Interleukin-7 receptor subunit alpha | polymer | 223 | 25431.8 | 1 | UniProt (P16872) Pfam (PF18447) Pfam (PF00041) In PDB | Mus musculus (mouse) | IL-7 receptor subunit alpha, IL-7R subunit alpha, IL-7R-alpha, IL-7RA |
3 | C | Cytokine receptor-like factor 2 | polymer | 212 | 22812.4 | 1 | UniProt (Q8CII9) Pfam (PF21604) Pfam (PF21605) In PDB | Mus musculus (mouse) | Cytokine receptor-like molecule 2, CRLM-2, Thymic stromal lymphopoietin protein receptor, TSLP receptor, TSLPR, Type I cytokine receptor delta 1 |
4 | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
A: 20 - 140 (UniProt: Q9JIE6)
B: 21 - 239 (UniProt: P16872)
C: 20 - 222 (UniProt: Q8CII9)
PDB | External Database | Details |
---|---|---|
Gln 123 | Asn 123 | engineered mutation |
Gly 141 | - | expression tag |
Thr 142 | - | expression tag |
Lys 143 | - | expression tag |
His 144 | - | expression tag |
His 145 | - | expression tag |
His 146 | - | expression tag |
His 147 | - | expression tag |
His 148 | - | expression tag |
His 149 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly 17 | - | expression tag |
Ser 18 | - | expression tag |
His 19 | - | expression tag |
Met 20 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gln 122 | Asn 122 | engineered mutation |
Val 179 | Ala 179 | conflict |
Gly 223 | - | expression tag |
Thr 224 | - | expression tag |
Lys 225 | - | expression tag |
His 226 | - | expression tag |
His 227 | - | expression tag |
His 228 | - | expression tag |
His 229 | - | expression tag |
His 230 | - | expression tag |
His 231 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 63354.1 | |
All* | Total formula weight | 63354.1 |