4LL1
The structure of the TRX and TXNIP complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Thioredoxin-interacting protein | polymer | 315 | 35021.4 | 2 | UniProt (Q9H3M7) Pfam (PF00339) Pfam (PF02752) In PDB | Homo sapiens (human) | Thioredoxin-binding protein 2, Vitamin D3 up-regulated protein 1 |
2 | B, D | Thioredoxin | polymer | 105 | 11718.4 | 2 | UniProt (P10599) Pfam (PF00085) In PDB | Homo sapiens (human) | Trx, ATL-derived factor, ADF, Surface-associated sulphydryl protein, SASP |
3 | water | water | 18.0 | 248 | Chemie (HOH) |
Sequence modifications
A, C: 3 - 317 (UniProt: Q9H3M7)
B, D: 1 - 105 (UniProt: P10599)
PDB | External Database | Details |
---|---|---|
Ser 120 | Cys 120 | engineered mutation |
Ser 170 | Cys 170 | engineered mutation |
Ser 205 | Cys 205 | engineered mutation |
Ser 267 | Cys 267 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ala 35 | Cys 35 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 93479.7 | |
All* | Total formula weight | 93479.7 |