4JVS

Crystal structure of LepB GAP domain from Legionella drancourtii in complex with Rab1-GDP and AlF3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Putative uncharacterized protein	polymer	310	35628.3	1	UniProt (G9EPL4) Pfam (PF18172) Pfam (PF18227) In PDB	Legionella drancourtii	GTPase activating protein
2	B	Ras-related protein Rab-1A	polymer	181	20483.2	1	UniProt (P62820) Pfam (PF00071) In PDB	Homo sapiens (human)	Ras superfamily of monomeric G protein, YPT1-related protein
3	A	ACETIC ACID	non-polymer		60.1	1	Chemie (ACY)
4	B	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
5	B	ALUMINUM FLUORIDE	non-polymer		84.0	1	Chemie (AF3)
6	B	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
7		water	water		18.0	4	Chemie (HOH)

Sequence modifications

A: 316 - 624 (UniProt: G9EPL4)

PDB	External Database	Details
Ser 311	-	expression tag
Gly 312	-	expression tag
Arg 313	-	expression tag
Pro 314	-	expression tag
Met 315	-	expression tag

B: 1 - 177 (UniProt: P62820)

PDB	External Database	Details
Ser -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
Pro 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56111.6
Non-Polymers*	Number of molecules	4
	Total formula weight	611.5
All*	Total formula weight	56723.1

*Water molecules are not included.