4JVS

Crystal structure of LepB GAP domain from Legionella drancourtii in complex with Rab1-GDP and AlF3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Putative uncharacterized protein	polymer	310	35628.3	1	UniProt (G9EPL4) Pfam (PF18172) Pfam (PF18227)	Legionella drancourtii	GTPase activating protein
2	B (B)	Ras-related protein Rab-1A	polymer	181	20483.2	1	UniProt (P62820) Pfam (PF00071)	Homo sapiens (human)	Ras superfamily of monomeric G protein, YPT1-related protein
3	C (A)	ACETIC ACID	non-polymer		60.1	1	Chemie (ACY)
4	D (B)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537)
5	E (B)	ALUMINUM FLUORIDE	non-polymer		84.0	1	Chemie (AF3) PubChem (2124)
6	F (B)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
7	G, H (A, B)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

A: 316 - 624 (UniProt: G9EPL4)

PDB	External Database	Details
Ser 311	-	expression tag
Gly 312	-	expression tag
Arg 313	-	expression tag
Pro 314	-	expression tag
Met 315	-	expression tag

B: 1 - 177 (UniProt: P62820)

PDB	External Database	Details
Ser -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
Pro 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56111.6
Non-Polymers*	Number of molecules	4
	Total formula weight	611.5
All*	Total formula weight	56723.1

*Water molecules are not included.