4JVS
Crystal structure of LepB GAP domain from Legionella drancourtii in complex with Rab1-GDP and AlF3
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY A 701 |
| Chain | Residue |
| A | ASP540 |
| A | SER541 |
| A | ASP546 |
| A | ILE547 |
| A | ARG579 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE GDP B 400 |
| Chain | Residue |
| B | LYS24 |
| B | SER25 |
| B | CYS26 |
| B | TYR36 |
| B | GLU38 |
| B | TYR40 |
| B | THR43 |
| B | ASN124 |
| B | LYS125 |
| B | ASP127 |
| B | LEU128 |
| B | SER154 |
| B | ALA155 |
| B | LYS156 |
| B | AF3401 |
| B | MG402 |
| A | ARG447 |
| B | GLY21 |
| B | VAL22 |
| B | GLY23 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE AF3 B 401 |
| Chain | Residue |
| A | ARG447 |
| B | SER20 |
| B | GLY21 |
| B | LYS24 |
| B | SER42 |
| B | THR43 |
| B | GLY69 |
| B | GLN70 |
| B | GDP400 |
| B | MG402 |
| B | HOH502 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 402 |
| Chain | Residue |
| B | SER25 |
| B | THR43 |
| B | THR67 |
| B | GDP400 |
| B | AF3401 |
Functional Information from PROSITE/UniProt
| site_id | PS00675 |
| Number of Residues | 14 |
| Details | SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. LLLiGDSGVGKscL |
| Chain | Residue | Details |
| B | LEU14-LEU27 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22416225, ECO:0000269|PubMed:22939626, ECO:0000269|PubMed:23588383, ECO:0000269|PubMed:23821544, ECO:0007744|PDB:2FOL, ECO:0007744|PDB:3SFV, ECO:0007744|PDB:3TKL, ECO:0007744|PDB:4FMB, ECO:0007744|PDB:4FMC, ECO:0007744|PDB:4FMD, ECO:0007744|PDB:4FME, ECO:0007744|PDB:4IRU, ECO:0007744|PDB:4JVS |
| Chain | Residue | Details |
| B | GLY18 | |
| B | ASN124 | |
| B | SER154 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22416225, ECO:0000269|PubMed:22939626, ECO:0000269|PubMed:23588383, ECO:0000269|PubMed:23821544, ECO:0007744|PDB:2FOL, ECO:0007744|PDB:3SFV, ECO:0007744|PDB:3TKL, ECO:0007744|PDB:4FMC, ECO:0007744|PDB:4FME, ECO:0007744|PDB:4IRU, ECO:0007744|PDB:4JVS |
| Chain | Residue | Details |
| B | TYR36 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22416225, ECO:0007744|PDB:3TKL |
| Chain | Residue | Details |
| B | ASP66 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylserine => ECO:0000269|Ref.9, ECO:0007744|PubMed:22223895 |
| Chain | Residue | Details |
| B | SER2 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: (Microbial infection) O-(2-cholinephosphoryl)serine => ECO:0000269|PubMed:21822290, ECO:0000269|PubMed:22158903 |
| Chain | Residue | Details |
| B | SER79 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | CARBOHYD: (Microbial infection) N-beta-linked (GlcNAc) arginine => ECO:0000269|PubMed:32504010 |
| Chain | Residue | Details |
| B | ARG72 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | CARBOHYD: (Microbial infection) N-beta-linked (GlcNAc) arginine => ECO:0000269|PubMed:32504010, ECO:0000269|PubMed:32974215 |
| Chain | Residue | Details |
| B | ARG74 | |
| B | ARG82 | |
| B | ARG111 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P51153 |
| Chain | Residue | Details |
| B | LYS49 | |
| B | LYS61 |
