4IG8
Structural basis for cytosolic double-stranded RNA surveillance by human OAS1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 2'-5'-oligoadenylate synthase 1 | polymer | 349 | 40135.2 | 1 | UniProt (P00973) Pfam (PF01909) Pfam (PF10421) | Homo sapiens (human) | (2-5')oligo(A) synthase 1, 2-5A synthase 1, E18/E16, p46/p42 OAS |
| 2 | B (B) | RNA (5'-R(*GP*GP*CP*UP*UP*UP*UP*GP*AP*CP*CP*UP*UP*UP*AP*UP*GP*C)-3') | polymer | 18 | 5664.3 | 1 | |||
| 3 | C (C) | RNA (5'-R(*GP*CP*AP*UP*AP*AP*AP*GP*GP*UP*CP*AP*AP*AP*AP*GP*CP*C)-3') | polymer | 18 | 5802.6 | 1 | |||
| 4 | D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | F (A) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 1 | Chemie (DTP) | |||
| 6 | G, H, I (A, B, C) | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence modifications
A: 1 - 347 (UniProt: P00973)
| PDB | External Database | Details |
|---|---|---|
| Gly 348 | - | expression tag |
| Pro 349 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 51602.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 539.8 | |
| All* | Total formula weight | 52141.9 |
