4I1O
Crystal structure of the Legionella pneumophila GAP domain of LepB in complex with Rab1b bound to GDP and BeF3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G | Ras-related protein Rab-1B | polymer | 181 | 20482.2 | 4 | UniProt (Q9H0U4) Pfam (PF00071) In PDB | Homo sapiens (human) | |
2 | B, D, F, H | LepB | polymer | 302 | 34131.9 | 4 | UniProt (Q5ZSM7) Pfam (PF18172) Pfam (PF18227) In PDB | Legionella pneumophila subsp. pneumophila | |
3 | A, C, E, G | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
4 | A, C, E, G | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 4 | Chemie (GDP) | |||
5 | A, C, E, G | BERYLLIUM TRIFLUORIDE ION | non-polymer | 66.0 | 4 | Chemie (BEF) | |||
6 | A, C, D, G | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 6 | Chemie (PEG) | |||
7 | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 3 - 174 (UniProt: Q9H0U4)
B, D, F, H: 317 - 618 (UniProt: Q5ZSM7)
PDB | External Database | Details |
---|---|---|
Gly 0 | - | expression tag |
His 1 | - | expression tag |
Met 2 | - | expression tag |
Leu 175 | - | expression tag |
Glu 176 | - | expression tag |
Val 177 | - | expression tag |
Leu 178 | - | expression tag |
Phe 179 | - | expression tag |
Gln 180 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 457 | Lys 457 | engineered mutation |
Ala 458 | Glu 458 | engineered mutation |
Ala 460 | Lys 460 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 218456.6 | |
Non-Polymers* | Number of molecules | 18 |
Total formula weight | 2770.8 | |
All* | Total formula weight | 221227.4 |