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4HD8

Crystal structure of human Sirt3 in complex with Fluor-de-Lys peptide and piceatannol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
NAD-dependent protein deacetylase sirtuin-3, mitochondrialpolymer28431484.21UniProt (Q9NTG7)
Pfam (PF02146)
Homo sapiens (human)hSIRT3, Regulatory protein SIR2 homolog 3, SIR2-like protein 3
2B
(F)
Fluor-de-Lys peptidepolymer4769.91
3C
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
4D
(A)
PICEATANNOLnon-polymer244.21Chemie (PIT)
5E
(A)
ISOPROPYL ALCOHOLnon-polymer60.11Chemie (IPA)
6F, G
(A, F)
waterwater18.0102Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight32254.1
Non-Polymers*Number of molecules3
Total formula weight369.7
All*Total formula weight32623.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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