4GNK
Crystal structure of Galphaq in complex with full-length human PLCbeta3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Guanine nucleotide-binding protein G(q) subunit alpha | polymer | 353 | 41538.2 | 2 | UniProt (P21279) Pfam (PF00503) In PDB | Mus musculus (mouse) | Guanine nucleotide-binding protein alpha-q |
2 | B, D | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 | polymer | 1235 | 139317.9 | 2 | UniProt (Q01970) Pfam (PF17787) Pfam (PF22631) Pfam (PF00388) Pfam (PF00387) Pfam (PF00168) Pfam (PF08703) In PDB | Homo sapiens (human) | Phosphoinositide phospholipase C-beta-3, Phospholipase C-beta-3, PLC-beta-3 |
3 | E | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 | polymer | 259 | 30347.6 | 1 | UniProt (Q01970) Pfam (PF08703) In PDB | Homo sapiens (human) | |
4 | A, C | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
5 | A, C | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 2 | Chemie (ALF) | |||
6 | A, C | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
7 | B, D | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
8 | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
B, D: 10 - 1234 (UniProt: Q01970)
PDB | External Database | Details |
---|---|---|
Met 0 | - | expression tag |
Ala 1 | - | expression tag |
His 2 | - | expression tag |
His 3 | - | expression tag |
His 4 | - | expression tag |
His 5 | - | expression tag |
His 6 | - | expression tag |
His 7 | - | expression tag |
Gly 8 | - | expression tag |
Thr 9 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 392059.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1221.1 | |
All* | Total formula weight | 393280.9 |