4E2J

X-Ray Crystal Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with mometasone furoate and TIF-2 coactivator fragment

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Ancestral Glucocorticoid Receptor 2	polymer	250	28774.4	2		synthetic construct
2	C, E	Nuclear receptor coactivator 2	polymer	12	1464.7	2	UniProt (Q15596) In PDB	Homo sapiens	NCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2
3	A, B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	A, B	MOMETASONE FUROATE	non-polymer		521.4	2	Chemie (MOF)
5	B	FORMIC ACID	non-polymer		46.0	1	Chemie (FMT)
6		water	water		18.0	151	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	60478.2
Non-Polymers*	Number of molecules	5
	Total formula weight	1273.1
All*	Total formula weight	61751.3

*Water molecules are not included.