4E2J
X-Ray Crystal Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with mometasone furoate and TIF-2 coactivator fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ancestral Glucocorticoid Receptor 2 | polymer | 250 | 28774.4 | 2 | synthetic construct | ||
| 2 | C, D (C, E) | Nuclear receptor coactivator 2 | polymer | 12 | 1464.7 | 2 | UniProt (Q15596) | Homo sapiens | NCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2 |
| 3 | E, I (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | F, G (A, B) | MOMETASONE FUROATE | non-polymer | 521.4 | 2 | Chemie (MOF) | |||
| 5 | H (B) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 6 | J, K, L, M (A, B, C, E) | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 60478.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1273.1 | |
| All* | Total formula weight | 61751.3 |
