4E2J
X-Ray Crystal Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with mometasone furoate and TIF-2 coactivator fragment
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 301 |
| Chain | Residue |
| A | GLY37 |
| A | ARG38 |
| A | PRO219 |
| A | GLU220 |
| A | MET221 |
| A | HOH424 |
| E | TYR747 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE MOF A 302 |
| Chain | Residue |
| A | GLY36 |
| A | GLN39 |
| A | ARG80 |
| A | PHE92 |
| A | MET108 |
| A | GLN111 |
| A | MET115 |
| A | PHE204 |
| A | CYS205 |
| A | THR208 |
| A | PHE218 |
| A | LEU32 |
| A | ASN33 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE MOF B 301 |
| Chain | Residue |
| B | MET29 |
| B | LEU32 |
| B | ASN33 |
| B | GLY36 |
| B | GLN39 |
| B | ARG80 |
| B | PHE92 |
| B | MET108 |
| B | MET115 |
| B | PHE204 |
| B | CYS205 |
| B | THR208 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT B 302 |
| Chain | Residue |
| B | TYR67 |
| B | SER68 |
| B | TRP69 |
| B | MET70 |
| B | SER71 |
| B | LEU202 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL B 303 |
| Chain | Residue |
| A | ARG54 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Motif: {"description":"LXXLL motif 3"} |
| Chain | Residue | Details |
