4BB2
Crystal structure of cleaved corticosteroid-binding globulin in complex with progesterone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CORTICOSTEROID-BINDING GLOBULIN | polymer | 340 | 37502.4 | 1 | UniProt (P08185) Pfam (PF00079) | HOMO SAPIENS (HUMAN) | CBG, SERPIN A6, TRANSCORTIN |
| 2 | B (B) | CORTICOSTEROID-BINDING GLOBULIN | polymer | 34 | 4083.9 | 1 | UniProt (P08185) | HOMO SAPIENS (HUMAN) | CBG, SERPIN A6, TRANSCORTIN |
| 3 | C, D, E, F, G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | H (A) | CYSTEINE | non-polymer | 121.2 | 1 | Chemie (CYS) | |||
| 5 | I (B) | PROGESTERONE | non-polymer | 314.5 | 1 | Chemie (STR) | |||
| 6 | J, K (A, B) | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A: 11 - 349 (UniProt: P08185)
| PDB | External Database | Details |
|---|---|---|
| Gly 10 | - | expression tag |
| Ala 126 | Lys 148 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 41586.3 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 746.0 | |
| All* | Total formula weight | 42332.3 |
