4BB2

Crystal structure of cleaved corticosteroid-binding globulin in complex with progesterone

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004867	molecular_function	serine-type endopeptidase inhibitor activity
A	0005615	cellular_component	extracellular space

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 1350

Chain	Residue
A	GLY61
A	ARG64

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1351

Chain	Residue
A	ARG260
A	ASP261
A	ASP261
A	EDO1352

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 1352

Chain	Residue
A	ARG260
A	EDO1351

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 1353

Chain	Residue
A	PHE309
A	SER310
A	ALA316
A	GLN317
A	LEU318
A	ALA307

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 1354

Chain	Residue
A	THR186
A	GLN187
A	ASN234

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site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CYS A 1385

Chain	Residue
A	CYS60
A	ARG64

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site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE STR B 1384

Chain	Residue
A	SER19
A	GLN232
A	ARG260
A	ASN264
A	HOH2060
B	PHE366
B	HIS368
B	TRP371
B	HOH2009

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Functional Information from PROSITE/UniProt

site_id	PS00284
Number of Residues	11
Details	SERPIN Serpins signature. LRFNQPFIImI

Chain	Residue	Details
B	LEU355-ILE365

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:18513745, ECO:0007744|PDB:2VDY

Chain	Residue	Details
B	HIS368
A	ASN264

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING:

Chain	Residue	Details
B	TRP371

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218

Chain	Residue	Details
A	ASN74

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN154

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site_id	SWS_FT_FI5
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine

Chain	Residue	Details
A	ASN238

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site_id	SWS_FT_FI6
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218

Chain	Residue	Details
A	ASN308

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site_id	SWS_FT_FI7
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952

Chain	Residue	Details
A	ASN347

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