4A5Y
Intermediate state of human kinesin Eg5 in complex with Ispinesib
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | KINESIN-LIKE PROTEIN KIF11 | polymer | 368 | 41055.6 | 3 | UniProt (P52732) Pfam (PF00225) | HOMO SAPIENS (HUMAN) | KINESIN-LIKE PROTEIN 1, KINESIN-LIKE SPINDLE PROTEIN HKSP, KINESIN-RELATED MOTOR PROTEIN EG5, THYROID RECEPTOR-INTERACTING PROTEIN 5, TR-INTERACTING PROTEIN 5, TRIP-5, EG5 |
| 2 | D, G, I (A, B, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 3 | E, M (A, C) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | F, H, N (A, B, C) | ISPINESIB MESILATE | non-polymer | 517.1 | 3 | Chemie (G7X) | |||
| 5 | J (C) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | K, L (C) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 7 | O, P, Q (A, B, C) | water | water | 18.0 | 342 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 123166.7 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 3117.9 | |
| All* | Total formula weight | 126284.7 |
