3UPC
A general strategy for the generation of human antibody variable domains with increased aggregation resistance
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | heavy chain variable domain | polymer | 113 | 12111.3 | 10 | Pfam (PF07686) UniProt (by SIFTS) (P01764) In PDB | Homo sapiens (human) | |
2 | A, D | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 2 | Chemie (1PE) | |||
3 | B | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
4 | C | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
5 | G, H, I | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 10 |
Total formula weight | 121113.4 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1315.5 | |
All* | Total formula weight | 122429.0 |