3QB1
Interleukin-2 mutant D10
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... (A, B, C, D, E...) | Interleukin-2 | polymer | 136 | 15727.2 | 8 | UniProt (P60568) Pfam (PF00715) | Homo sapiens (human) | IL-2, T-cell growth factor, TCGF |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 133 (UniProt: P60568)
PDB | External Database | Details |
---|---|---|
Ala -2 | - | expression tag |
Asp -1 | - | expression tag |
Pro 0 | - | expression tag |
His 74 | Gln 94 | engineered mutation |
Phe 80 | Leu 100 | engineered mutation |
Asp 81 | Arg 101 | engineered mutation |
Val 85 | Leu 105 | engineered mutation |
Val 86 | Ile 106 | engineered mutation |
Phe 92 | Ile 112 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 125817.2 | |
All* | Total formula weight | 125817.2 |