3P57
Crystal structure of the p300 TAZ2 domain bound to MEF2 on DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, I...) | Myocyte-specific enhancer factor 2A | polymer | 90 | 10628.3 | 6 | UniProt (Q02078) Pfam (PF00319) | Homo sapiens (human) | Serum response factor-like protein 1 |
| 2 | G, I, K (E, G, K) | DNA (5'-D(*A*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3') | polymer | 15 | 4600.0 | 3 | Synthetic construct | ||
| 3 | H, J, L (F, H, L) | DNA (5'-D(*TP*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3') | polymer | 15 | 4573.0 | 3 | Synthetic construct | ||
| 4 | M (P) | Histone acetyltransferase p300 | polymer | 112 | 12957.5 | 1 | UniProt (Q09472) Pfam (PF02135) | Homo sapiens (human) | p300 HAT, E1A-associated protein p300 |
| 5 | N, O, P (P) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 6 | AA, BA, CA, Q, R... (K, L, P, A, B...) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
P: 4 - 113 (UniProt: Q09472)
| PDB | External Database | Details |
|---|---|---|
| His 2 | - | expression tag |
| Met 3 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 13 |
| Total formula weight | 104246.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 196.2 | |
| All* | Total formula weight | 104442.8 |
