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3P57

Crystal structure of the p300 TAZ2 domain bound to MEF2 on DNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, I...Myocyte-specific enhancer factor 2Apolymer9010628.36UniProt (Q02078)
Pfam (PF00319)
In PDB
Homo sapiens (human)Serum response factor-like protein 1
2E, G, KDNA (5'-D(*A*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*GP*A)-3')polymer154600.03Synthetic construct
3F, H, LDNA (5'-D(*TP*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*TP*T)-3')polymer154573.03Synthetic construct
4PHistone acetyltransferase p300polymer11212957.51UniProt (Q09472)
Pfam (PF02135)
In PDB
Homo sapiens (human)p300 HAT, E1A-associated protein p300
5PZINC IONnon-polymer65.43Chemie (ZN)
6waterwater18.0262Chemie (HOH)
Sequence modifications
P: 4 - 113 (UniProt: Q09472)
PDBExternal DatabaseDetails
His 2-expression tag
Met 3-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains13
Total formula weight104246.6
Non-Polymers*Number of molecules3
Total formula weight196.2
All*Total formula weight104442.8
*Water molecules are not included.

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PDB entries from 2024-09-11

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