3LTG

Crystal structure of the Drosophila Epidermal Growth Factor Receptor ectodomain complexed with a low affinity Spitz mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, C)	Epidermal growth factor receptor	polymer	601	67970.9	2	UniProt (P04412) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843)	Drosophila melanogaster	Gurken receptor, Protein torpedo, Drosophila relative of ERBB
2	C (D)	Protein spitz	polymer	52	6012.9	1	UniProt (Q01083)	Drosophila melanogaster

Sequence modifications

A, C: 1 - 589 (UniProt: P04412)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Glu 38	Lys 137	conflict
Gly 230	Ala 329	conflict
Cys 232	Ser 331	conflict
Leu 359	Arg 458	conflict
Asn 493	Thr 592	conflict
His 590	-	expression tag
His 591	-	expression tag
His 592	-	expression tag
His 593	-	expression tag
His 594	-	expression tag
His 595	-	expression tag

D: 1 - 51 (UniProt: Q01083)

PDB	External Database	Details
Asp 52	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	141954.7
All*	Total formula weight	141954.7

*Water molecules are not included.