3LTG

Crystal structure of the Drosophila Epidermal Growth Factor Receptor ectodomain complexed with a low affinity Spitz mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
D	0005154	molecular_function	epidermal growth factor receptor binding
D	0007173	biological_process	epidermal growth factor receptor signaling pathway
D	0048018	molecular_function	receptor ligand activity

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CeCaiGfmGQrC

Chain	Residue	Details
D	CYS35-CYS46

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site_id	PS01186
Number of Residues	12
Details	EGF_2 EGF-like domain signature 2. CeCaiGFmgqr....C

Chain	Residue	Details
D	CYS35-CYS46

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PDB","id":"3LTF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	8
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PDB","id":"3I2T","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LTF","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	44
Details	Domain: {"description":"EGF-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU00076","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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