3LNZ

Crystal structure of human MDM2 with a 12-mer peptide inhibitor PMI (N8A mutant)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, C, E, G, I...)	E3 ubiquitin-protein ligase Mdm2	polymer	85	10044.9	8	UniProt (Q00987) Pfam (PF02201)		p53-binding protein Mdm2, Oncoprotein Mdm2, Double minute 2 protein, Hdm2
2	B, D, F, H, J... (B, D, F, H, J...)	12-mer peptide inhibitor	polymer	12	1384.5	8
3	Q, R, S, T, U... (A, C, E, G, I...)	CHLORIDE ION	non-polymer		35.5	8	Chemie (CL)
4	AA, BA, CA, DA, EA... (C, D, E, F, G...)	water	water		18.0	702	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	91435.4
Non-Polymers*	Number of molecules	8
	Total formula weight	283.6
All*	Total formula weight	91719.0

*Water molecules are not included.