3IGQ

Crystal structure of the extracellular domain of a bacterial pentameric ligand-gated ion channel

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Glr4197 protein	polymer	201	22872.7	6	UniProt (Q7NDN8) Pfam (PF02931)	Gloeobacter violaceus
2	AA, G, K, O, S... (F, A, B, C, D...)	ACETIC ACID	non-polymer		60.1	6	Chemie (ACY)
3	BA, H, L, P, T... (F, A, B, C, D...)	SODIUM ION	non-polymer		23.0	6	Chemie (NA)
4	CA, I, M, Q, U... (F, A, B, C, D...)	MERCURY (II) ION	non-polymer		200.6	6	Chemie (HG)
5	DA, J, N, R, V... (F, A, B, C, D...)	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
6	EA, FA, GA, HA, IA... (A, B, C, D, E...)	water	water		18.0	408	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 2 - 193 (UniProt: Q7NDN8)

PDB	External Database	Details
Ala 1	-	expression tag
Gly 116	Phe 158	engineered mutation
Thr 119	Tyr 161	engineered mutation
Glu 120	Pro 162	engineered mutation
Ser 121	Phe 163	engineered mutation
Gly 194	-	expression tag
Gly 195	-	expression tag
His 196	-	expression tag
His 197	-	expression tag
His 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag
His 201	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	137236.2
Non-Polymers*	Number of molecules	24
	Total formula weight	1914.5
All*	Total formula weight	139150.7

*Water molecules are not included.