3I5D
Crystal structure of the ATP-gated P2X4 ion channel in the closed, apo state at 3.5 Angstroms (R3)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | P2X purinoceptor | polymer | 356 | 40194.8 | 3 | UniProt (Q6NYR1) Pfam (PF00864) UniProt (by SIFTS) (F8W463) | Danio rerio (leopard danio zebra danio zebra fish) | |
| 2 | D, E (D, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | F, G, H, I, J... (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) |
Sequence modifications
A, B, C: 28 - 381 (UniProt: Q6NYR1)
| PDB | External Database | Details |
|---|---|---|
| Gly 26 | - | expression tag |
| Ser 27 | - | expression tag |
| Arg 252 | His 252 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 120584.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2212.1 | |
| All* | Total formula weight | 123645.3 |
