3H06

Crystal structure of the binding domain of the AMPA subunit GluR2 bound to the willardiine antagonist, UBP282

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (G, B, E, H, J...)	Glutamate receptor 2	polymer	258	28835.3	8	UniProt (P19491) Pfam (PF10613) Pfam (PF00060)	Rattus norvegicus	GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2
2	I, J, K, L, M... (G, B, E, H, J...)	4-({3-[(2R)-2-amino-2-carboxyethyl]-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)benzoic acid	non-polymer		333.3	8	Chemie (VBP)
3	Q, R, S, T, U... (G, B, E, H, J...)	water	water		18.0	292	Chemie (HOH)

Sequence modifications

G, B, E, H, J, L, N, P: 4 - 117 (UniProt: P19491)
G, B, E, H, J, L, N, P: 120 - 261 (UniProt: P19491)

PDB	External Database	Details
Gly 118	-	linker
Thr 119	-	linker

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.