3H06
Crystal structure of the binding domain of the AMPA subunit GluR2 bound to the willardiine antagonist, UBP282
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | G, B, E, H, J... | Glutamate receptor 2 | polymer | 258 | 28835.3 | 8 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) In PDB | Rattus norvegicus | GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2 |
2 | G, B, E, H, J... | 4-({3-[(2R)-2-amino-2-carboxyethyl]-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl}methyl)benzoic acid | non-polymer | 333.3 | 8 | Chemie (VBP) | |||
3 | water | water | 18.0 | 292 | Chemie (HOH) |
Sequence modifications
G, B, E, H, J, L, N, P: 4 - 117 (UniProt: P19491)
G, B, E, H, J, L, N, P: 120 - 261 (UniProt: P19491)
G, B, E, H, J, L, N, P: 120 - 261 (UniProt: P19491)
PDB | External Database | Details |
---|---|---|
Gly 118 | - | LINKER |
Thr 119 | - | LINKER |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 230682.6 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 2666.4 | |
All* | Total formula weight | 233348.9 |