3FG4
Crystal structure of Delta413-417:GS I805A LOX
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Allene oxide synthase-lipoxygenase protein | polymer | 696 | 79366.9 | 4 | UniProt (O16025) Pfam (PF01477) Pfam (PF00305) | Plexaura homomalla (black sea rod) | Allene oxide synthase, Hydroperoxidehydrase, Arachidonate 8-lipoxygenase |
| 2 | BB, E, KA, Z (D, A, C, B) | FE (II) ION | non-polymer | 55.8 | 4 | Chemie (FE2) | |||
| 3 | AA, AB, CB, F, G... (B, C, D, A) | CALCIUM ION | non-polymer | 40.1 | 8 | Chemie (CA) | |||
| 4 | BA, DB, H, NA (B, D, A, C) | ARACHIDONIC ACID | non-polymer | 304.5 | 4 | Chemie (ACD) | |||
| 5 | CA, DA, EA, EB, FA... (B, D, A, C) | ACETIC ACID | non-polymer | 60.1 | 21 | Chemie (ACY) | |||
| 6 | GA, HA, IA, IB, JB... (B, D, A, C) | GLYCEROL | non-polymer | 92.1 | 19 | Chemie (GOL) | |||
| 7 | JA, LB, W, ZA (B, D, A, C) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 8 | MB, NB, OB, PB (A, B, C, D) | water | water | 18.0 | 1582 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 374 - 1066 (UniProt: O16025)
| PDB | External Database | Details |
|---|---|---|
| Met 368 | - | expression tag |
| His 369 | - | expression tag |
| His 370 | - | expression tag |
| His 371 | - | expression tag |
| His 372 | - | expression tag |
| His 373 | - | expression tag |
| - | Trp 413 | deletion |
| - | Phe 414 | deletion |
| - | His 415 | deletion |
| Gly 413 | Asn 416 | engineered mutation |
| Ser 414 | Asp 417 | engineered mutation |
| Ile 782 | Val 782 | SEE REMARK 999 |
| Ala 805 | Ile 805 | engineered mutation |
| Ile 963 | Val 963 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 317467.7 | |
| Non-Polymers* | Number of molecules | 60 |
| Total formula weight | 4914.6 | |
| All* | Total formula weight | 322382.2 |
