3ERD
HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH DIETHYLSTILBESTROL AND A GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1 NR BOX II PEPTIDE
Replaces: 2ERDEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | ESTROGEN RECEPTOR ALPHA | polymer | 261 | 29850.2 | 2 | UniProt (P03372) Pfam (PF00104) | Homo sapiens (human) | OESTROGEN RECEPTOR, ER LBD |
| 2 | C, D (C, D) | GLUCOCORTICOID RECEPTOR INTERACTING PROTEIN 1 | polymer | 13 | 1579.9 | 2 | GenBank (1853980) UniProt (by SIFTS) (Q15596) | Homo sapiens (human) | GRIP1 |
| 3 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | F, G (A, B) | DIETHYLSTILBESTROL | non-polymer | 268.4 | 2 | Chemie (DES) | |||
| 5 | H, I (B) | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
| 6 | J, K, L (A, B, D) | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A, B: 294 - 554 (UniProt: P03372)
| PDB | External Database | Details |
|---|---|---|
| Met 294 | Ser 294 | cloning artifact |
| Asp 295 | Pro 295 | cloning artifact |
| Pro 296 | Leu 296 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62860.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 692.3 | |
| All* | Total formula weight | 63552.4 |
