3D4B
Crystal structure of Sir2Tm in complex with Acetyl p53 peptide and DADMe-NAD+
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | NAD-dependent deacetylase | polymer | 246 | 27569.8 | 1 | UniProt (Q9WYW0) Pfam (PF02146) In PDB | Thermotoga maritima | Regulatory protein SIR2 homolog |
| 2 | D | Acetyl P53 peptide | polymer | 9 | 1116.4 | 1 | |||
| 3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | A | 5'-O-[(R)-{[(R)-{[(3R,4R)-1-(3-carbamoylbenzyl)-4-hydroxypyrrolidin-3-yl]methoxy}(hydroxy)phosphoryl]methyl}(hydroxy)phosphoryl]adenosine | non-polymer | 657.5 | 1 | Chemie (DZD) | |||
| 5 | water | water | 18.0 | 142 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28686.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 722.9 | |
| All* | Total formula weight | 29409.1 |
