3C6M
Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Spermine synthase | polymer | 381 | 43002.9 | 4 | UniProt (P52788) Pfam (PF17950) Pfam (PF17284) Pfam (PF01564) In PDB | Homo sapiens (human) | Spermidine aminopropyltransferase, SPMSY |
2 | A, B, C, D | SPERMINE | non-polymer | 202.3 | 4 | Chemie (SPM) | |||
3 | A, B, C, D | 5'-DEOXY-5'-METHYLTHIOADENOSINE | non-polymer | 297.3 | 4 | Chemie (MTA) | |||
4 | water | water | 18.0 | 300 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 5 - 366 (UniProt: P52788)
PDB | External Database | Details |
---|---|---|
Met -14 | - | expression tag |
Gly -13 | - | expression tag |
Ser -12 | - | expression tag |
Ser -11 | - | expression tag |
His -10 | - | expression tag |
His -9 | - | expression tag |
His -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
Ser -4 | - | expression tag |
Ser -3 | - | expression tag |
Gly -2 | - | expression tag |
Leu -1 | - | expression tag |
Val 0 | - | expression tag |
Pro 1 | - | expression tag |
Arg 2 | - | expression tag |
Gly 3 | - | expression tag |
Ser 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 172011.5 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1998.7 | |
All* | Total formula weight | 174010.2 |