2ZU6
crystal structure of the eIF4A-PDCD4 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, D, F (A, C, D, F) | Eukaryotic initiation factor 4A-I | polymer | 388 | 44317.9 | 4 | UniProt (P60842) Pfam (PF00270) Pfam (PF00271) | Homo sapiens (Human) | eIF-4A-I, eIF4A-I, ATP-dependent RNA helicase eIF4A-1 |
| 2 | B, E (B, E) | Programmed cell death protein 4 | polymer | 307 | 34671.3 | 2 | UniProt (Q53EL6) Pfam (PF02847) | Homo sapiens (Human) | Nuclear antigen H731-like, Neoplastic transformation inhibitor protein, Protein 197/15a |
| 3 | G, H, J (A, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | I, K (A, D) | ACETIC ACID | non-polymer | 60.1 | 2 | Chemie (ACY) | |||
| 5 | L, M, N, O, P (A, B, C, D, E) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence modifications
A, C, D, F: 20 - 406 (UniProt: P60842)
| PDB | External Database | Details |
|---|---|---|
| Met 19 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 246614.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 306.3 | |
| All* | Total formula weight | 246920.5 |
