2ZKU

Structure of hepatitis C virus NS5B polymerase in a new crystal form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Genome polyprotein	polymer	576	64103.5	4	UniProt (Q99AU2) Pfam (PF00998) UniProt (by SIFTS) (P26663) In PDB	Hepatitis C virus subtype 1b
2	A, B, C, D	ACETIC ACID	non-polymer		60.1	7	Chemie (ACY)
3	A, B	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
4		water	water		18.0	2107	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 570 (UniProt: Q99AU2)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	256413.9
Non-Polymers*	Number of molecules	14
	Total formula weight	1065.0
All*	Total formula weight	257478.9

*Water molecules are not included.