2ZKU

Structure of hepatitis C virus NS5B polymerase in a new crystal form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Genome polyprotein	polymer	576	64103.5	4	UniProt (Q99AU2) Pfam (PF00998) UniProt (by SIFTS) (P26663)	Hepatitis C virus subtype 1b
2	E, F, L, M, N... (A, B, C, D)	ACETIC ACID	non-polymer		60.1	7	Chemie (ACY)
3	G, H, I, J, K... (A, B)	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
4	S, T, U, V (A, B, C, D)	water	water		18.0	2107	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 570 (UniProt: Q99AU2)

PDB	External Database	Details
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	256413.9
Non-Polymers*	Number of molecules	14
	Total formula weight	1065.0
All*	Total formula weight	257478.9

*Water molecules are not included.