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2ZEB

Potent, Nonpeptide Inhibitors of Human Mast Cell Tryptase

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Tryptase beta 2polymer24327265.14UniProt (Q6B052)
Pfam (PF00089)
UniProt (by SIFTS) (Q15661)
Homo sapiens (Human)
2E, F, G, H
(A, B, C, D)
1-(1'-{[3-(methylsulfanyl)-2-benzothiophen-1-yl]carbonyl}spiro[1-benzofuran-3,4'-piperidin]-5-yl)methanaminenon-polymer424.64Chemie (11M)
3I, J, K, L
(A, B, C, D)
waterwater18.0299Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight109060.5
Non-Polymers*Number of molecules4
Total formula weight1698.3
All*Total formula weight110758.8
*Water molecules are not included.

248942

PDB entries from 2026-02-11

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