2TNF
1.4 A RESOLUTION STRUCTURE OF MOUSE TUMOR NECROSIS FACTOR, TOWARDS MODULATION OF ITS SELECTIVITY AND TRIMERISATION
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | PROTEIN (TUMOR NECROSIS FACTOR ALPHA) | polymer | 156 | 17272.5 | 3 | UniProt (P06804) Pfam (PF00229) | Mus musculus (house mouse) | TNF-ALPHA, CACHECTIN |
| 2 | D (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 3 | E (B) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 1 | Chemie (IPA) | |||
| 4 | F, G, H (A, B, C) | water | water | 18.0 | 240 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 51817.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 182.2 | |
| All* | Total formula weight | 51999.7 |
