2RAX

Crystal structure of Borealin (20-78) bound to Survivin (1-120)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, E, X)	Baculoviral IAP repeat-containing protein 5	polymer	123	14117.0	3	UniProt (O15392) Pfam (PF00653)	Homo sapiens (human)	Apoptosis inhibitor survivin, Apoptosis inhibitor 4
2	B, D, F (B, F, Y)	Borealin	polymer	68	8265.5	3	UniProt (Q53HL2) Pfam (PF10444)	Homo sapiens (human)	Dasra-B, hDasra-B, Cell division cycle-associated protein 8, Pluripotent embryonic stem cell-related gene 3 protein
3	G, H, I (A, E, X)	ZINC ION	non-polymer		65.4	3	Chemie (ZN)

Sequence modifications

A, E, X: 1 - 120 (UniProt: O15392)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

B, F, Y: 20 - 78 (UniProt: Q53HL2)

PDB	External Database	Details
Met 19	-	expression tag
Trp 79	-	expression tag
Ser 80	-	expression tag
His 81	-	expression tag
Pro 82	-	expression tag
Gln 83	-	expression tag
Phe 84	-	expression tag
Glu 85	-	expression tag
Lys 86	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	67147.6
Non-Polymers*	Number of molecules	3
	Total formula weight	196.2
All*	Total formula weight	67343.8

*Water molecules are not included.