2RAX
Crystal structure of Borealin (20-78) bound to Survivin (1-120)
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 341 |
| Chain | Residue |
| A | CYS57 |
| A | CYS60 |
| A | HIS77 |
| A | CYS84 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN E 341 |
| Chain | Residue |
| E | CYS57 |
| E | CYS60 |
| E | HIS77 |
| E | CYS84 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN X 341 |
| Chain | Residue |
| X | CYS60 |
| X | HIS77 |
| X | CYS84 |
| X | CYS57 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:17956729, ECO:0007744|PDB:2QFA |
| Chain | Residue | Details |
| A | CYS57 | |
| X | CYS60 | |
| X | HIS77 | |
| X | CYS84 | |
| A | CYS60 | |
| A | HIS77 | |
| A | CYS84 | |
| E | CYS57 | |
| E | CYS60 | |
| E | HIS77 | |
| E | CYS84 | |
| X | CYS57 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine; by AURKC => ECO:0000269|PubMed:27332895 |
| Chain | Residue | Details |
| A | SER20 | |
| E | SER20 | |
| X | SER20 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 15 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000269|PubMed:20826784 |
| Chain | Residue | Details |
| A | LYS23 | |
| E | LYS115 | |
| X | LYS23 | |
| X | LYS90 | |
| X | LYS110 | |
| X | LYS112 | |
| X | LYS115 | |
| A | LYS90 | |
| A | LYS110 | |
| A | LYS112 | |
| A | LYS115 | |
| E | LYS23 | |
| E | LYS90 | |
| E | LYS110 | |
| E | LYS112 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine; by CDK1 and CDK15 => ECO:0000269|PubMed:11069302, ECO:0000269|PubMed:24866247, ECO:0007744|PubMed:18691976 |
| Chain | Residue | Details |
| A | THR34 | |
| E | THR34 | |
| X | THR34 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine; by CK2; in vitro => ECO:0000269|PubMed:21252625 |
| Chain | Residue | Details |
| A | THR48 | |
| E | THR48 | |
| X | THR48 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine; by AURKB => ECO:0000269|PubMed:14610074 |
| Chain | Residue | Details |
| A | THR117 | |
| E | THR117 | |
| X | THR117 |
