2RAX
Crystal structure of Borealin (20-78) bound to Survivin (1-120)
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 341 |
| Chain | Residue |
| A | CYS57 |
| A | CYS60 |
| A | HIS77 |
| A | CYS84 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN E 341 |
| Chain | Residue |
| E | CYS57 |
| E | CYS60 |
| E | HIS77 |
| E | CYS84 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN X 341 |
| Chain | Residue |
| X | CYS60 |
| X | HIS77 |
| X | CYS84 |
| X | CYS57 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 210 |
| Details | Repeat: {"description":"BIR"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17956729","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QFA","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphoserine; by AURKC","evidences":[{"source":"PubMed","id":"27332895","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 15 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"20826784","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphothreonine; by CDK1 and CDK15","evidences":[{"source":"PubMed","id":"11069302","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24866247","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18691976","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphothreonine; by CK2; in vitro","evidences":[{"source":"PubMed","id":"21252625","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphothreonine; by AURKB","evidences":[{"source":"PubMed","id":"14610074","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
