2QQN
Neuropilin-1 b1 Domain in Complex with a VEGF-Blocking Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neuropilin-1 | polymer | 159 | 18004.4 | 1 | UniProt (O14786) Pfam (PF00754) | Homo sapiens (human) | Vascular endothelial cell growth factor 165 receptor, CD304 antigen |
| 2 | B (H) | Antibody heavy chain | polymer | 230 | 24289.3 | 1 | Pfam (PF07654) UniProt (by SIFTS) (P01857) | Homo sapiens (human) | |
| 3 | C (L) | Antibody light chain | polymer | 214 | 23305.8 | 1 | Pfam (PF07654) UniProt (by SIFTS) (P01834) | Homo sapiens (human) | |
| 4 | D, E, F (A, H, L) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | G, H, I (A, H, L) | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
A: 273 - 427 (UniProt: O14786)
| PDB | External Database | Details |
|---|---|---|
| Gly 269 | - | expression tag |
| Ser 270 | - | expression tag |
| His 271 | - | expression tag |
| Met 272 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 65599.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 186.2 | |
| All* | Total formula weight | 65785.7 |
